Monthly intake of 3 grams of saffron is proved beneficial for health, yet this amount must not reach 5 grams as it can lead to adverse consequences on body. Note, consumption of 5 grams of saffron in one intake can cause death!
Excessive dosage of safranal in saffron can create toxic effect. Some recent studies suggest that due to the peculiar climate and soil properties in Iran and especially in Khorasaun, the Saffron cultivated in this region contains less amount of safranal compared to the saffrons from other parts of the world.